If You Aren’t Incorporating Retinoids into Your Nightly Routine, You Should Be

By Peachy

Breaking Down the Science of our Retinoid Formula

The term “retinoid” might take you back to your high school days, combating acne with a cream that made your skin extremely dry, irritated, and flaky. Or perhaps your mind immediately shifts to the retinol cream sitting in your medicine cabinet, causing you to wonder if they’re the same thing. In either case, you are not alone! 

We’ll break down the science of our prescription retinoid formula, so you can better understand how retinoids work and why they should be a key component of your skincare routine.*

The Main Event: Tretinoin

First and foremost, the term “retinoid” is used to describe vitamin A derivatives that include both over-the-counter retinols and prescription-only retinoids. At Peachy, we use the retinoid tretinoin, a naturally occuring vitamin A derivative. Tretinoin is available by prescription only, meaning it has been rigorously tested and approved by the FDA. There is a plethora of data showing that consistent retinoid use minimizes fine lines, evens skin tone, smooths texture, and decreases acne. All good things!

You may be asking yourself, “Doesn’t retinol do the same thing?” The fact is, we don’t have the same breadth of clinical proof for retinols as we do for retinoids, so it’s hard to say how the effects of retinol compare to that of retinoids. What we do know is that due to differences in molecular structure, retinol is 20 times less potent than tretinoin, thereby making prescription retinoids the most certain way to prevent wrinkles and achieve your best skin.

The Amplifier: Vitamin C

Within our prescription retinoid formula, we’ve included ingredients to amplify the retinoid’s performance. Vitamin C is a potent antioxidant that can prevent changes associated with photoaging, or damage caused by the sun. In this way, it works in tandem with the tretinoin to reduce the appearance of wrinkles and patchy hyperpigmentation. The end result is smoother skin in both texture and tone!  

The Soothers: Hyaluronic Acid and Niacinamide (aka Vitamin B3)

As some people may experience skin irritation, redness, and flakiness when using a retinoid, our retinoid cream also includes ingredients that combat these potential side effects. Hyaluronic acid and niacinamide help lock in skin’s moisture and prevent irritation. In addition, since irritation, redness, and flakiness are more likely to occur when one’s skin is not yet acclimated to high concentrations of retinoids, we start our patients with low doses in order to build tolerance over time. The end result is a nightly cream proven to even out your skin’s texture and tone with a minimal risk of excessive dryness.

*Retinoids cannot be used if you are pregnant, trying to become pregnant, or breastfeeding.

Citations

Hubbard, B. A., Unger, J. G., & Rohrich, R. J. Reversal of skin aging with topical retinoids. Plast Reconstr Surg, 2014 Apr; 133(4):481e-90e. doi: 10.1097/PRS.0000000000000043

Serri, R., & Iorizzo, M. Cosmeceuticals: focus on topical retinoids in photoaging. Clin Dermatol. 2008 Nov-Dec; 26(6): 633-5. doi: 10.1016/j.clindermatol.2007.09.016.

Boswell, C. Skincare science: Update on topical retinoids. Aesthet Surg J. 2006 Mar-Apr;26(2):233-9. doi: 10.1016/j.asj.2006.02.003.

Kang S, Duell EA, Fisher GJ, et al. Application of retinol to human skin in vivo induces epidermal hyperplasia and cellular retinoid binding proteins characteristic of retinoic acid but without measurable retinoic acid levels or irritation. J Invest Dermatol. 1995 Oct;105(4):549-56. doi:10.1111/1523-1747.ep12323445

Chiu, A., & Kimball, A. B.Topical vitamins, minerals and botanical ingredients as modulators of environmental and chronological skin damage. Br J Dermatol. 2003 Oct;149(4):681-91. doi:10.1046/j.1365-2133.2003.05540.x

Manela-Azulay, M., & Bagatin, E. Cosmeceuticals vitamins. Clin Dermatol. 2009 Sep-Oct; 27(5):469-74. doi: 10.1016/j.clindermatol.2009.05.010. 

Papakonstantinou, E., Roth, M., & Karakiulakis, G. Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. 2012 Jul 1;4(3):253-8. doi: 10.4161/derm.21923.